Crestor, containing rosuvastatin, is a widely prescribed oral medication for lowering elevated cholesterol levels, especially for patients who have high cholesterol levels through diet and exercise. It belongs to a class of drugs known as “statins” and is primarily used to lower LDL cholesterol levels, while increasing HDL cholesterol levels.
The rising prevalence of infectious disorders, obesity, and psychological trauma are significant drivers of the Crestor market. These factors contribute to market growth and expansion in the region.
Current Crestor market growth is driven by several key factors:
In addition, the increasing prevalence of obesity, a fact of life, is also a key driver. Obesity can lead to a variety of health issues for both individuals and couples. Obesity can exacerbate various conditions such as insulin resistance, coronary artery disease, and hypertension. The rising body mass index (BMI) is a significant factor driving the market growth during the forecast period.
The global Crestor market is driven by several key regional factors:
North America is expected to continue its dominance during the market's growth. The region's high incidence of cardiovascular diseases and chronic obstructive pulmonary disease (COPD) are key drivers of the North American Crestor market.
The Crestor market is available in various distribution channels:
These channels are further bolstered by initiatives such as:
These initiatives support the market's growth.
The Crestor market is a major player in the North American Crestor market. Players like Lupin, AstraZeneca, and Sanofi are among the top manufacturers of Crestor. These companies are also focusing on improving manufacturing processes, enhancing product safety, and expanding distribution channels. However, the global Crestor market is experiencing limited signs of decline.
The competitive landscape of the Crestor market is characterized by the need for consistent supply of generic drugs. This allows for more consistent demand for Crestor. For instance, the generic Crestor brand of Crestor is manufactured by Lupin, while the brand Crestor is manufactured by Sanofi.
Crestor works by reducing a certain enzyme within the body that produces cholesterol. It belongs to a class of medications called statins.
Cholesterol is a form of lipid, a waxy substance that helps your body make cells, vitamins, and certain hormones. It is not inherently bad. Your liver produces an enzyme that synthesizes cholesterol to help with the above healthy functions. Additional cholesterol is introduced to the body through certain foods like meat, poultry, and dairy products.
There are two types of cholesterol: high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs). LDLs carry cholesterol throughout the body, delivering cholesterol to cells that need it. HDLs carry excess LDLs back to the liver, where they are broken down and flushed from the body. While LDLs play a key role in cell health, they build up when the body has more cholesterol than the cells need. This buildup turns into plaque in the arteries (blood vessels). As plaque covers the artery walls, the blood vessels become narrow. This makes it harder for blood to flow through the body, which can lead to heart disease and heart failure.
Statins work by reducing the production of cholesterol in the liver, which lowers the overall cholesterol levels in the body. Not only do statins decrease levels of LDLs in the body, but they can also raise the level of HDLs in the body. In effect, they keep the body from making too much of the “bad” cholesterol that builds up in arteries while increasing the amount of “good” cholesterol that carries the “bad” out of the body. This dual action has been shown, along with diet and exercise, to lower overall cholesterol levels in patients effectively.
Crestor (Rosuvastatin) is a generic medication that works by inhibiting the enzyme that carries cholesterol from the heart to the body. It does this by reduced the production of about a third of the cholesterol in the liver. This total}}Cholesterol is a waxy substance that can be detected in blood in levels that arein the same order as cholesterol in your bloodfound in some low- cholesterol foods. In other words, levels are the same for total levels found in the free-living world. In high-density lipoprotein (LDL) cholesterol levels, total levels can be significantly lower. In other words, total levels are the same in the free-living world as in the high-density lipoprotein (HDL) cholesterol levels.When the production of cholesterol in the body is reduced, the amount of lipophilic triglycerides ( fats) that carry cholesterol back to the body is reduced. This lipophilic status allows the body to eliminate more of the cholesterol in the liver, thus lowering the overall cholesterol levels in the body and leading to fewer cardiovascular events. The total}}Rosuvastatin is agenericreductase inhibitor. This medication is able to block cholesterol production from low-density lipoprotein (LDL) cholesterol to the high-density lipoprotein (HDL) cholesterol level. However, it is important to note that this medication should only be used under the guidance of a healthcare provider. It should not be used in patients who are allergic to any of the ingredients found in rosuvastatin.
Generic cholesterol medication should not be used in combination with other medications that can increase or decrease the production of cholesterol in the body. These include other oral or injectable medicines, such as simvastatin (Lupron, Invaal, others) or lovastatin (Altocor, FetzOL); or drugs used to treat high blood pressure, such as atorvastatin (Lipitor, in Ezetran) or rosuvastatin (Crestor, in Janssen). In one study, lovastatin (Lovenox) was shown to be associated with an increased risk of stroke in patients with high cholesterol levels. Simvastatin (Lovenox) is also associated with an increased risk of heart attack and stroke. If lovastatin is prescribed alongside lovastatin, it should be used with caution in patients with a prior diagnosis of a heart condition, especially in combination with simvastatin or lovastatin.
Crestor should not be used in patients with a history of heart problems, such as unstable angina or heart failure, those with a prior history of heart bypass surgery, coronary artery disease, or if taking a medication that contains calcium. Crestor can increase the risk of stroke, heart attack, and blood clots. Patients with a family history of heart disease, high or low blood pressure, or if taking certain other medicines should avoid Crestor.
AstraZeneca's drug, known as Rosuvastatin Calcium (Crestor), is now available in the UK for the treatment of.
In a recent article posted at the British Medical Journal, the drug's maker, AstraZeneca, explained that the UK government's decision to restrict its market to patients who have been prescribed this drug for heart failure has also led to a sharp drop in cost.
The drug is a member of the cholesterol-lowering drug statins, which are widely prescribed for high-risk patients, such as those with high LDL (low-density lipoprotein) levels, as well as for those with high triglycerides, high blood pressure and high levels of glucose. Rosuvastatin Calcium is a member of the class of drugs known as P-glycoprotein (G protein-coupled receptor) inhibitors, which work by blocking the actions of an enzyme called G protein-coupled receptors.
This means that cholesterol levels are reduced in patients with heart failure who take statins and in those who have had heart failure since the onset of symptoms. The drug is not approved for use in the UK for this indication, as its cost has been slashed by half over the past three years by the government's current regulations.
The article in the British Medical Journal, which was posted on the British National Formulary, said that the UK's current regulations in this area are now being revised to allow patients to have access to the drug and to be prescribed it for their conditions.
In the article, Dr Andrew Taylor-Pacey, AstraZeneca's chief executive, explained that the UK's current restrictions on the sale of statins are "very limited," making them "an important step forward in the treatment of patients with high cholesterol," he added.
The article further said that the drug could be used to treat the symptoms of heart failure, such as shortness of breath and fatigue, which have been associated with it.
The drug's manufacturers, including AstraZeneca, have expressed concern that the UK's new rules could have led to a drop in its revenue from sales of the drug.
The UK government has also announced restrictions on sales of the drug to people who have been prescribed the drug for heart failure.
The drug's manufacturer, Sanofi Aventis, has said that the decision was based on "considerable evidence" and "the availability of data to support the decision," it added.
Sanofi's UK office told MedPageBullet that the decision "remains subject to approval by the Health Secretary."
AstraZeneca says it will not comment on specific details of the decision on the drug's impact on cost and future results.Reviewed bySteven S. hier
Reviewed by MedPageBullet bySteven S.Updated onAugust 15, 2015
Last updated on July 15, 2015
AstraZeneca is a leading pharmaceutical company headquartered in Cambridge, the UK. The UK's largest biotechnology company, AstraZeneca, operates as a leader in the areas of biosimilar, biotechnology and biopharmaceuticals. The company has global operations in over 100 countries, including the US.
AstraZeneca's brand and product portfolio includes cardiovascular drugs, diabetes, cancer and respiratory treatments.
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The British Medical Journal is a non-profit academic medical journal. Our mission is to provide the highest standard of medical advice and research by providing a comprehensive, evidence-based, safe and trustworthy medical journal. The medical journal has a dedicated page with resources for all medical questions and concerns. For more information, visit us at.AstraZeneca says it will not comment on specific details of the decision on the drug's impact on cost and future resultsThe UK's current regulations on pharmaceutical sales were in place earlier this year to allow patients to have access to the drug.
Crestor works by reducing a certain enzyme within the body that causes cholesterol to be released. It belongs to a class of medications called statins.
Statin drugsare a class of medications that work by inhibiting the action of a smallcrafted natural substance called statin.
These pills come in pills that contain the drug statin. They come in pill forms that you can take with or without food. The pill form of the drug will help you to swallow it whole with water.
IngredientsEach tablet contains the active ingredient, cholesterol, and other active ingredients that help to make this medicine effective.
They come in pill form that you can take with or without food.
Each tablet contains the drug statin.
Organic acid (OA) is an amino acid that helps to make this medicine effective.Each tablet contains the active ingredient, OA, that helps to reduce bad cholesterol and raise good cholesterol.
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